Misoprostol is an effective and safe uterotonic for the prevention and treatment of postpartum hemorrhage (PPH). A 600-mcg oral dose of misoprostol has been shown to prevent PPH in community-based randomized controlled trials. An 800-mcg sublingual dose of misoprostol appears to be a good first-line treatment for controlling PPH. Adverse effects after use of misoprostol for PPH prevention or treatment may include shivering and fever. These effects are transient, resolve on their own, and are not life threatening. Misoprostol can play an important role in settings with limited access to oxytocin, and where there is no other option for PPH care.

Access the abstract.

Published:
Oct. 2012
Type:
Staff Publication
Topic:
Postpartum Hemorrhage
Authors:
Abbas, Dina, Raghavan, Sheila, Winikoff, Beverly, Raghavan, S., Abbas, D., Winikoff, B.

PDF

Not all resources are available in all formats. Select language to check availability.