Gynuity Health Projects


Prophylactic compared with therapeutic Ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial

This article reports on a study that sought to compare the efficacy of two ibuprofen regimens (therapeutic vs. prophylactic) in first-trimester abortion. Women assigned to both groups reported high levels of pain. Prophylactic use of ibuprofen did not appear to lessen the length or severity of pain.

Obstet Gynecol. 2013 Sep;122(3):558-64. doi: 10.1097/AOG.0b013e31829d5a33.
Abstract available at:

  • Topic: Medical Abortion
  • Type: Staff Publication
  • Author: Raymond, E.G., Weaver, M.A., Louie, K.S., Dean, G., Porsch, L., Lichtenberg, E.S., Ali, R., Arnesen, M.
  • Published: June 2013