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Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women not exposed to oxytocin during labour: A double-blind, randomised, non-inferiority trial
This article describes the results of a clinical trial seeking to evaluate the use of misoprostol compared to standard oxytocics for treatment of postpartum hemorrhage in women who were not previously exposed to oxytocin during labor. The results demonstrate that misoprostol may be a suitable first-line treatment alternative for this indication particularly in settings in which use of oxytocin is not feasible. Read the abstract at The Lancet (Jan 2010), Vol 375(9710), pp 210 – 216.