Jill Durocher

Cervical Preparation Before Dilation and Evacuation Using Adjunctive Misoprostol or Mifepristone Com

November 6th, 2015
Staff Publication
Medical Abortion
Winikoff, Beverly, Goldberg, A.B., Fortin, J.A., Drey, E.A., Dean, G., Lichtenberg, E.S., Bednarek, P.H., Chen, B.A., Dutton, C., McKetta, S., Maurer, R., Fitzmaurice, G.M.

This double-blind, three-arm, multicenter, randomized trial compared overnight osmotic dilators alone, dilators plus 400 micrograms buccal misoprostol 3 hours preoperatively, and dilators plus 200 mg oral mifepristone during dilator placement for dilation and evacuation for second trimester abortion. Despite no difference in operative time, adjunctive mifepristone facilitates later dilation and evacuation compared with osmoticdilators alone and is better tolerated than misoprostol.

Access the abstract.