Jill Durocher

Comment: Randomised Trials of Medical Abortion Provide Some But Not All the Answers

August 27th, 2022
Medication Abortion
Winikoff, B., Lohr, P.A.

The Lancet; 2022 August 27; Vol. 400 (10353): 638-639; doi:10.1016/S0140-6736(22)01609-9

Comment: A medical abortion is the termination of pregnancy by medications without surgery. The most recommended regimen up to 10 weeks’ gestation uses 200 mg oral mifepristone followed 1–2 days later by 800 μg misoprostol. Mifepristone was initially registered for use under the supervision of a doctor up to 7 weeks of gestation. Since then, hundreds of studies have been carried out to extend availability of the method, including flexible regimens, higher gestational age thresholds, and self-management of medical abortion at home. These studies consistently show high effectiveness, safety, and acceptability.

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