Research Summary: Effectiveness and Safety of Misoprostol-Only for First-Trimester Medication Abortion: An Updated Systematic Review and Meta-Analysis

A summary of the key findings from a systematic review of available data on the effectiveness and safety of misoprostol-only for medication abortion in the first 12 weeks of gestation. This latest study updates our prior review published in 2019.

Note Medication abortion with mifepristone and misoprostol has indisputable advantages over using misoprostol only and is generally recognized as more efficacious. Policymakers should advocate for greater access to mifepristone.