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Two distinct oral routes of misoprostol in mifepristone medical abortion

Published
December 4th, 2008
Type
Staff Publication
Topic
Medical Abortion
Authors
Winikoff, Beverly, Shannon, Caitlin, Dzuba, Ilana, Winikoff, B., Dzuba, I.G., Creinin, M.D., Crowden, W.A., Goldberg, A.B., Gonzales, J., Howe, M., Moskowitz, J., Prine, L., Shannon, C.

This article reports on a study designed to evaluate the efficacy, safety, and acceptability of oral immediately swallowed and buccal misoprostol 800 mcg after mifepristone 200 mg for terminating pregnancy through 63 days since the last menstrual period (LMP). The results demonstrate that buccal misoprostol 800 mcg after mifepristone 200 mg is a good option for medical abortion through 63 days since the LMP. Oral misoprostol 800 mcg is also a safe and effective alternative, although success rates diminish with increasing gestational age.

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