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Jill Durocher

Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women receiving prophylactic oxytocin: a double-blind, randomised, non-inferiority trial

Published
January 16th, 2010
Type
Publication
Topic
Postpartum Hemorrhage
Authors
Blum, J., Winikoff, B., Raghavan, R., Dabash, R., Cherine Ramadan, M., Dilbaz, B., Dao, B., Durocher, J., Yalvac, S., Diop, A., Dzuba, I.G., Ngoc, N.T.N.
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This article describes the results of a clinical trial seeking to evaluate the use of misoprostol compared to standard oxytocics for treatment of postpartum hemorrhage in women receiving prophylactic oxytocin during labor. The results demonstrate that misoprostol is clinically equivalent to oxytocin when used to stop excessive post-partum bleeding suspected to be due to uterine atony under these circumstances. The Lancet; January 16, 2010; Vol. 375(9710):217-223; doi:https://doi.org/10.1016/S0140-6736(09)61923-1